Colored Petri nets to Model and Simulate Biological Systems

نویسندگان

  • Fei Liu
  • Monika Heiner
چکیده

Petri nets have become an effective formalism to model biological systems. However, attempts to simulate biological systems by low-level Petri nets are restricted to relatively small models, and they tend to grow quickly for modeling complex systems, which makes it more difficult to manage and understand the nets. Motivated by this, we propose a colored Petri net-based framework for modeling, simulating, and analyzing complex biological systems. We give the definitions of biochemically interpreted colored qualitative Petri nets (QPN) and colored stochastic Petri nets (SPN) and describe their functionalities and features implemented in the Petri net tool Snoopy. We use two examples, the cooperative ligand binding and the repressilator, to demonstrate how to construct and simulate QPN and SPN models, respectively.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Accessibility Evaluation in Biometric Hybrid Architecture for Protecting Social Networks Using Colored Petri Nets

In the last few decades, technological progress has been made important information systems that require high security, Use safe and efficient methods for protecting their privacy. It is a major challenge to Protecting vital data and the ability to threaten attackers. And this has made it important and necessary to be sensitive to the authentication and identify of individuals in confidential n...

متن کامل

Accessibility Evaluation in Biometric Hybrid Architecture for Protecting Social Networks Using Colored Petri Nets

In the last few decades, technological progress has been made important information systems that require high security, Use safe and efficient methods for protecting their privacy. It is a major challenge to Protecting vital data and the ability to threaten attackers. And this has made it important and necessary to be sensitive to the authentication and identify of individuals in confidential n...

متن کامل

Encoding Higher Level Extensions of Petri Nets in Answer Set Programming

Answering realistic questions about biological systems and pathways similar to the ones used by text books to test understanding of students about biological systems is one of our long term research goals. Often these questions require simulation based reasoning. To answer such questions, we need formalisms to build pathway models, add extensions, simulate, and reason with them. We chose Petri ...

متن کامل

Modeling of Continuous Systems Using Modified Petri Nets

Due to the changes which may occur in their parameters, systems are usually demonstrated by some subsystems for different conditions. This paper employs Modified Petri Nets (MPN) to model theses subsystems and makes it simple to analyze them. In this method, first, the continuous transfer function is converted to a discrete transfer function and then, by MPN, system is modeled and analyzed. All...

متن کامل

Using Interval Petri Nets and Timed Automata for Diagnosis of Discrete Event Systems (DES)

A discrete event system (DES) is a dynamic system that evolves in accordance with the abrupt occurrence, at possibly unknown irregular intervals, of physical events. Because of the special nature of these systems, different tools are currently used for their analysis, design and modeling. The main focus of this paper is the presentation of a new modeling approach of Discrete Event Systems. The ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010